Mast cell activation is the release of histamine and other inflammatory mediators from mast cells. Mast cells are immune cells that are found throughout the body, but they are especially concentrated in the skin, lungs, and digestive tract.
Mast cells can be activated by a variety of triggers, including:
- Allergens (such as pollen, dust mites, and pet dander)
- Infections (such as viruses and bacteria)
- Medications (such as aspirin and ibuprofen)
- Physical stimuli (such as heat, cold, and pressure)
- Emotional stress
Check your susceptibility with the MCAS questionnaire
